- Chris Anthony
(Host)
- Amber Arnold
(Brooke Myers)
- Landon Arnold
(Cousin "Scrubb" Moseley)
- Natalie Babbitt
(Jenny Roberts)
- Parley Baer
("Uncle" Joe Finneman)
- Tracy Bassett
(Julie)
- Camilla Belle
(Aubrey Shepard)
- Brooke Bellessi
(Traci Needlemeyer)
- Kendre Berry
(Marvin Washington)
- Carol Bilger
(Mary Barclay)
- Earl Boen
(Dr. Regis Blackgaard, Edwin Blackgaard)
- Chuck Bolte
(George Barclay)
- Erin Bolte
(Melanie Jacobs)
- Sage Bolte
(Robyn Jacobs)
- Steve Bridges
(Jesus and various other voices)
- Courtney Brown
(Tamika Washington)
- David Buller
(Billy MacPherson)
- Steve Burns
(Rodney Rathbone, Robert Mitchell)
- Corey Burton
(Cryin' Bryan Dern, Brock Peterson, Walter Shakespeare, Mr. Burton, Jesus,
and many other voices)
- Sara Buskirk
(Courtney Vincent)
- Jordan Calloway
(Marvin Washington)
- Niles Calloway
(Xavier Washington)
- Joseph Cammarato
(Oscar)
- Nathan Carlson
(Richard Maxwell)
- Chris Castile
(Nick Mulligan, Zachary Sellars)
- Townsend Coleman
(Jason Whittaker)
- Randy Crenshaw
(Lance Lincoln, Don Iowa)
- Aria Curzon
(Mandy Straussberg)
- Jim Custer (Young Whit)
- Joe Dammann
(Eric Myers)
- Jennifer Day
(Brenda Perry)
- Walker Edmiston (Tom Riley, Bart Rathbone)
- Kyle Ellison
(Sam Johnson)
- Jeff Ellison
(David Straussberg)
- Gabriel Encarnacion
(Lawrence Hodges)
- Bernard Erhard
(Armitage Shanks)
- Blake Ewing
(Nathaniel Graham)
- Joan Gerber
(Audrey Nelson, Vivian Birch)
- Brandon Gilberstadt
(Jared DeWhite)
- Andrew Gillespie
(Henry Thomas)
- James D. Griffin
(Jimmy Barclay)
- D. J. Harner
(Jana Whittaker-Dowd)
- Jess Harnell
(Wooton Bassett, Bennett Charles)
- Pam Hayden (Katrina Shanks, Doris Rathbone)
- Caroline Hennessy
(Ellen Shepard)
- Paul Herlinger
(John Avery Whittaker)
- Jerry Houser
(Jerry Morton, Jellyfish, Ben Shepard)
- Matt Hurwitz
(Mr. Jefferson)
- Azure Janosky
(Donna Barclay)
- Danielle Judovits
(Aubrey Shepard)
- Kris Kachurak
(Dwayne Oswald)
- David Kirkwood
(Henry Ross)
- Mark Christopher
Lawrence (Ed Washington)
- Katie Leigh
(Connie Kendall)
- Phil Lollar
(Dale Jacobs)
- Donald Long
(Jack Davis)
- Genni (Mullen)
Long (Lucy Cunningham-Schultz)
- Erin Love
(Erica Clark)
- Dave Madden
(Bernard Walton)
- Maggie Malloy
(June Kendall, Mary Barclay)
- Kenneth Mars
(Captain Quinn, Fred Holstein, Sir William)
- Paul McCusker
(Philip Glossman)
- Brad McMurray
(Steven Schmidt)
- Diane Michelle
("Doc" Morton)
- Erin Morales
(Jesse Morales)
- Curt Morse
(Curt Morse)
- Bill Myers
(Mike Mulligan)
- Nicole Myers
(Lisa Mulligan)
- Jennifer Naimo
(Mrs. Jefferson)
- Christie Nimitz
(Tasha Forbes)
- Natalie O'Hare
(Jenny Whittaker, Mary Hopkins)
- Jordan Orr (Grady)
- Corey Padnos
(Trent DeWhite)
- Adam Pavlakovich
(Cal Jordan)
- Sarah Pilgreen
(Bethany Shepard)
- Scarlett Pomers
(Sarah Prachett)
- Chad Reisser
(Monty Whittaker-Dowd, Digger Digwillow)
- Peter Renaday
(*Saint Paul, *Saint Patrick, *John the Baptist)
- Lydia Reissmueller
(Marsha)
- Will Ryan
(Eugene Meltsner, Harlow Doyle, Officer O'Ryan, Officer David Harley)
- Lauren Schaffel
(Liz Horton)
- Danny Schmittler
(Danny Schmidt)
- Mark Shillinger
(Charles Edward Thompson)
- Hal Smith
(John Avery Whittaker)
- Christopher
Snell (Arthur Dent)
- Fabio Stephens
(Curt Stevens, Tony)
- Kara Stokke
(Cheryl McCormick)
- Shawn Svoboda
(Rusty Gordon)
- Travis Tedford
(Alex Jefferson)
- J Karen Thomas
(Elaine Washington)
- Audrey Wasilewski (Katrina Shanks)
- Janet Waldo
(Maureen Hodges, Joanne Woodston Allen)
- Alan Young
(Jack Allen)
